Myocardial Alterations in Adrenoreceptors After Ventricular Unloading with a Pulsatile vs a Nonpulsatile Device~!2010-02-15~!2010-05-06~!2010-06-10~!
نویسندگان
چکیده
منابع مشابه
Myocardial Alterations in Adrenoreceptors After Ventricular Unloading with a Pulsatile vs a Nonpulsatile Device
We have recently shown that ventricular unloading with an implantable left ventricular assist device (LVAD) leads to improved calcium handling and membrane integrity and redistribution of alpha adrenoreceptors (AARs) and betaadrenoreceptors (BARs). Here, we used fluorescence deconvolution microscopy to examine the effect of LVAD type (pulsatile vs non-pulsatile) on upregulation and redistributi...
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BACKGROUND Ventricular assist devices (VADs) are an accepted therapy for patients with end-stage heart failure. The implantable devices that are available produce a pulsatile flow and are very large. In 6 patients, beginning in November 1998, we started to use the continuous-flow implantable DeBakey VAD device, which weighs 93 g. To detect the flow in peripheral vessels, we measured transcrania...
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The refinement of mechanical cardiac assist devices over the past 50 years largely has been driven by the clinical imperatives to provide reliable circulatory support to patients waiting for cardiac allografts (bridge to transplant) or longterm support for patients with very advanced heart failure (destination therapy). In the course of increasing success with these applications, investigators ...
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Technetium-99m-pyrophosphate (99mTc-PYP) has been used, in combination with thallium-201, to estimate the site and extent of myocardial infarcts. We report a case of acute myocardial infarction with severe coronary disease in which the distribution of 99mTc-PYP was extensive. A 78-year-old man presented with dyspnea, and a diagnosis of non-ST-segment elevation acute myocar...
متن کاملEffects of continuous-flow versus pulsatile-flow left ventricular assist devices on myocardial unloading and remodeling.
BACKGROUND Continuous-flow left ventricular assist devices (LVAD) are increasingly used for patients with end-stage heart failure (HF). We analyzed the effects of ventricular decompression by continuous-flow versus pulsatile-flow LVADs on myocardial structure and function in this population. METHODS AND RESULTS Sixty-one patients who underwent LVAD implantation as bridge-to-transplant were an...
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ژورنال
عنوان ژورنال: The Open Cardiovascular and Thoracic Surgery Journal
سال: 2010
ISSN: 1876-5335
DOI: 10.2174/1876533501003010001